Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.73 |
| ▸ | MMP3 | P08254 | 12/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590424 | 0.90 | MMP2 (0.59) | MMP2MMP3SIGMAR1GPR119 | |
| SCHEMBL6590251 | 0.87 | MMP2 (0.71) | MMP2MMP3GPR119ADAM10 | |
| SCHEMBL6586215 | 0.84 | MMP3 (1.00) | MMP2MMP3 | |
| SCHEMBL6587727 | 0.83 | MMP3 (0.76) | MMP2MMP3GPR119ADAM10 | |
| SCHEMBL6589722 | 0.83 | MMP3 (0.81) | MMP2MMP3 | |
| SCHEMBL6590023 | 0.82 | MMP2 (0.77) | MMP2MMP3SIGMAR1 | |
| SCHEMBL6583128 | 0.81 | MMP2 (0.73) | MMP2MMP3 | |
| SCHEMBL6585982 | 0.81 | MMP3 (0.86) | MMP2MMP3 | |
| SCHEMBL6584456 | 0.81 | MMP3 (1.00) | MMP2MMP3GPR119ADAM10 | |
| SCHEMBL6586903 | 0.81 | MMP3 (1.00) | MMP2MMP3ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |