SCHEMBL658739

SCHEMBL658739

COc1cccc2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 6/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
MAPT P10636 5/20 0.40
HTT P42858 3/20 0.40
FTO Q9C0B1 2/20 0.40
LMNA P02545 2/20 0.40
USP2 O75604 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
SMAD3 P84022 1/20 0.40
PRMT1 Q99873 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
TXNRD1 Q16881 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8757874 0.88 FTO (0.41) CYP3A4ALDH1A1HPGDHSD17B10MEN1
SCHEMBL5532838 0.85 NPC1 (0.44) CYP3A4ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL10709421 0.84 CYP3A4 (0.41) CYP3A4ALDH1A1HPGDHSD17B10MEN1
SCHEMBL11666220 0.84 FTO (0.59) CYP3A4ALDH1A1HPGDHSD17B10MEN1
SCHEMBL1524853 0.81 PRKCA (0.47) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL10358710 0.81 CYP3A4 (0.45) CYP3A4ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL15141720 0.81 INPPL1 (0.41) CYP3A4ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL1603421 0.80 MAPT (0.42) CYP3A4ALDH1A1HPGDHSD17B10MEN1
SCHEMBL9557864 0.80 ALDH1A1 (0.38) CYP3A4ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL9712154 0.78 ALDH1A1 (0.36) CYP3A4ALDH1A1HPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070119450-A1 Medication holder TIANDA PHARMACEUTICALS (AUSTRALIA) PTY LIMITED (AU) 2007-05-31 US claimed
EP-1675636-A1 MEDICATION HOLDER Medi-Stream Pty Ltd. (AU) 2006-07-05 EP claimed
WO-2005028006-A1 MEDICATION HOLDER MEDI-STREAM PTY LTD (AU) 2005-03-31 WO claimed
EP-1073425-A1 FIBRINOGEN COATED DROPLETS OF LIQUID HYDROPHOBIC PHASES THE UNIVERSITY OF CINCINNATI (US) 2001-02-07 EP claimed
WO-1999055314-A1 FIBRINOGEN COATED DROPLETS OF LIQUID HYDROPHOBIC PHASES UNIVERSITY OF CINCINNATI (US) 1999-11-04 WO claimed
US-5560933-A INCLUDES BIOCOMPATIBLE POLYMER CAPABLE OF BEING CROSSLINKED BY DISULFIDE BONDS TO PRODUCE SHELL VIVORX PHARMACEUTICALS, INC. (US) 1996-10-01 US claimed
US-5439686-A Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor VIVORX PHARMACEUTICALS, INC. (US) 1995-08-08 US claimed
US-4399686-A FOR ANAESTHETICS, SUBSTRATE COATED WITH SILICONE GLYCOL COPOLYMER ENGSTROM MEDICAL AB (SE) 1983-08-23 US claimed
EP-4740953-A1 PHARMACEUTICAL COMPOSITION COMPRISING CO2 FOR USE IN THE TREATMENT OF CONDITIONS ASSOCIATED WITH HEADACHE Migrainy UG (haftungsbeschränkt) (DE) 2026-05-13 EP disclosed
WO-2026087643-A1 COMPOSITION AND DEVICE COMPRISING CO2 FOR THERAPEUTIC USES MIGRAINY UG (DE) 2026-04-30 WO disclosed
US-12378301-B2 B1SP fusion protein therapeutics, methods, and uses THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-08-05 US disclosed
US-RE49758-E1 Stabilised protein compositions based on semifluorinated alkanes NOVALIQ GMBH (DE) 2023-12-19 US disclosed
EP-3313526-B1 B1SP FUSION PROTEIN THERAPEUTICS, METHODS, AND USES UNIV BRITISH COLUMBIA (CA) 2023-11-08 EP disclosed
CN-115671084-B Application of methoxyflurane in preparation of medicines for resisting echinococcosis 四川大学华西医院 2023-09-15 CN disclosed
US-4172709-A Bacteria filters with transparent housings BECTON, DICKINSON AND COMPANY (US) 1979-10-30 US disclosed
US-4171962-A Bacteria filters with transparent housings BECTON, DICKINSON AND COMPANY (US) 1979-10-23 US disclosed
US-4133656-A Bacteria filters with transparent housings BECTON, DICKINSON AND COMPANY (US) 1979-01-09 US disclosed
US-4063913-A Bacteria filters with transparent housings BECTON, DICKINSON AND COMPANY (US) 1977-12-20 US disclosed
US-4058120-A Vaporizer carousel for anesthesia machine AIR PRODUCTS AND CHEMICALS, INC. (US) 1977-11-15 US disclosed
US-3954893-A INHALATION ANESTHETICS W. R. GRACE & CO. (US) 1976-05-04 US disclosed