Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658477 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL658478 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL658069 | 0.74 | CYP2A6 (0.38) | PRKDCLMNA | |
| SCHEMBL31303112 | 0.72 | AOC3 (0.42) | PRKDCAOC3 | |
| SCHEMBL25234795 | 0.72 | AOC3 (0.42) | PRKDCAOC3 | |
| SCHEMBL30191342 | 0.71 | LMNA (0.37) | PRKDCLMNA | |
| SCHEMBL112640 | 0.71 | LMNA (0.37) | PRKDCLMNA | |
| SCHEMBL660309 | 0.71 | ERN1 (0.37) | PRKDCLMNA | |
| SCHEMBL28953827 | 0.69 | PRKDC (0.33) | PRKDCLMNA | |
| SCHEMBL658808 | 0.69 | ERN1 (0.34) | PRKDCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | disclosed |
| EP-4448534-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118339167-A | Microbiocidal bicyclic heterocyclic derivatives | 先正达农作物保护股份公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023110869-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110869-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | NOX1, CASP1, CYP1A1 | PRKDC 1103/4885AOC3 107/4885LMNA 3592/4885 |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | PRKDC 738/4885AOC3 3163/4885LMNA 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.