Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658477 | 1.00 | MEN1 (0.31) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL658741 | 0.79 | PRKDC (0.33) | — | |
| SCHEMBL660820 | 0.76 | ALOX12 (0.45) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL660821 | 0.76 | ALOX12 (0.45) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL659017 | 0.74 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL659016 | 0.74 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL28168693 | 0.72 | MAPT (0.34) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL30127063 | 0.71 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL659677 | 0.70 | KMT2A (0.44) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL659676 | 0.70 | KMT2A (0.44) | MEN1ALDH1A1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | disclosed |
| EP-4448534-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118339167-A | Microbiocidal bicyclic heterocyclic derivatives | 先正达农作物保护股份公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023110869-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | NOX1, CASP1, CYP1A1 | MEN1 3301/4885ALDH1A1 954/4885KMT2A 4317/4885 |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | MEN1 296/4885ALDH1A1 490/4885KMT2A 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.