Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587549 | 1.00 | ALDH1A1 (0.68) | ALDH1A1GLAPKMHTTLMNA | |
| SCHEMBL6587537 | 1.00 | ALDH1A1 (0.68) | ALDH1A1GLAPKMHTTLMNA | |
| SCHEMBL10875329 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HTTLMNAGAASMN1; SMN2 | |
| SCHEMBL10875320 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HTTLMNAGAASMN1; SMN2 | |
| SCHEMBL16592442 | 0.83 | PKM (0.78) | ALDH1A1GLAPKMHTTLMNA | |
| SCHEMBL16592441 | 0.83 | PKM (0.78) | ALDH1A1GLAPKMHTTLMNA | |
| SCHEMBL10874425 | 0.81 | HTT (0.56) | ALDH1A1HTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10874419 | 0.81 | HTT (0.56) | ALDH1A1HTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL6585742 | 0.80 | EPHX1 (0.53) | ALDH1A1LMNAEPHX1GAASMN1; SMN2 | |
| SCHEMBL6587522 | 0.80 | EPHX1 (0.53) | ALDH1A1LMNAEPHX1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |