Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585742 | 1.00 | EPHX1 (0.53) | EPHX1LPAR1ALDH1A1HPGDMEN1 | |
| SCHEMBL6080072 | 0.90 | EPHX1 (0.52) | EPHX1LPAR1ALDH1A1HPGDMEN1 | |
| SCHEMBL6587736 | 0.89 | MEN1 (0.57) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6587740 | 0.89 | MEN1 (0.57) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6587300 | 0.84 | LPAR1 (0.49) | LPAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6587301 | 0.84 | LPAR1 (0.49) | LPAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6585901 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDPOLBSMN1; SMN2GAA | |
| SCHEMBL6585904 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDPOLBSMN1; SMN2GAA | |
| SCHEMBL6587549 | 0.80 | ALDH1A1 (0.68) | EPHX1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6587541 | 0.80 | ALDH1A1 (0.68) | EPHX1ALDH1A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |