Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ME2 | P23368 | 2/20 | 0.55 |
| ▸ | ME1 | P48163 | 2/20 | 0.55 |
| ▸ | ME3 | Q16798 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587595 | 0.81 | HTR1A (0.51) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL7131839 | 0.78 | NPC1 (0.86) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL2289613 | 0.76 | KMT2A (0.61) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL2824683 | 0.76 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL3796071 | 0.76 | MAPT (0.80) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL4314831 | 0.75 | HTR1A (0.41) | KMT2AMAPTALDH1A1POLBHTR1A | |
| SCHEMBL3799761 | 0.75 | KMT2A (0.67) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL8984794 | 0.74 | NPC1 (0.69) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL14747850 | 0.74 | NPC1 (0.73) | KMT2AMAPTMEN1ALDH1A1ME2 | |
| SCHEMBL3801360 | 0.74 | NPC1 (0.73) | KMT2AMAPTMEN1ALDH1A1ME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | disclosed |