Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | AXL | P30530 | 3/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587599 | 0.81 | KMT2A (0.60) | HTR1AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6586745 | 0.76 | HTR1A (0.48) | HTR1AALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL4314831 | 0.75 | HTR1A (0.41) | HTR1AALDH1A1ALOX15HSD17B10KMT2A | |
| SCHEMBL6589346 | 0.75 | HTR1A (0.58) | HTR1AALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6586642 | 0.75 | HTR1A (0.55) | HTR1AALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4422938 | 0.74 | NPC1 (0.53) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL4555805 | 0.72 | MAPT (0.48) | HTR1AALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL6589366 | 0.71 | HTR1A (0.61) | HTR1AMEN1KMT2AAKT1 | |
| SCHEMBL6161203 | 0.71 | MAPK1 (0.40) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL6586356 | 0.71 | HTR1A (0.44) | HTR1AAKT1RBP4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | disclosed |