Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.79 |
| ▸ | MMP3 | P08254 | 8/20 | 0.79 |
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | MMP14 | P50281 | 2/20 | 0.68 |
| ▸ | CTPS1 | P17812 | 6/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590101 | 0.91 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587030 | 0.91 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6585076 | 0.88 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| Dimethylamine SCHEMBL6974207 | 0.87 | MMP3 (0.97) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6585851 | 0.81 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6584994 | 0.80 | MMP2 (0.85) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586804 | 0.80 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6973528 | 0.80 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586134 | 0.79 | MMP3 (0.83) | MMP2MMP3MMP1MMP9MMP14 | |
| Hydrochloric Acid SCHEMBL6971643 | 0.79 | MMP3 (0.98) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |