Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587809 | 1.00 | KMT2A (0.48) | KMT2AMAPTALDH1A1MAPK1HTT | |
| SCHEMBL6587301 | 0.89 | LPAR1 (0.49) | KMT2AMAPTALDH1A1HTTMEN1 | |
| SCHEMBL6587300 | 0.89 | LPAR1 (0.49) | KMT2AMAPTALDH1A1HTTMEN1 | |
| SCHEMBL6587740 | 0.84 | MEN1 (0.57) | KMT2AMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL6587736 | 0.84 | MEN1 (0.57) | KMT2AMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL14721362 | 0.81 | ALDH1A1 (0.52) | KMT2AMAPTALDH1A1MAPK1HTT | |
| SCHEMBL6586201 | 0.80 | CREBBP (0.41) | KMT2AMAPTALDH1A1MAPK1HTT | |
| SCHEMBL6584410 | 0.80 | LMNA (0.48) | ALDH1A1HTTPOLBLMNAKDM4E | |
| SCHEMBL6584406 | 0.80 | LMNA (0.48) | ALDH1A1HTTPOLBLMNAKDM4E | |
| SCHEMBL6080904 | 0.78 | MEN1 (0.56) | KMT2AMAPTALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |