Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | IL6 | P05231 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099928 | 0.86 | IL6 (0.58) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11814248 | 0.79 | IL6 (0.59) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13201517 | 0.79 | ELANE (0.40) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18028834 | 0.79 | HCRTR1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL17469473 | 0.79 | S1PR3 (0.60) | RAB9AMAPTPIK3CGS1PR3 | |
| SCHEMBL29236673 | 0.78 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19102856 | 0.76 | CSNK1D (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL615340 | 0.76 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4390043 | 0.75 | PIK3CG (0.66) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14075973 | 0.74 | RAB9A (0.74) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118186779-A | Sizing agent for enhancing PBO fiber composite material interface, and preparation method and application thereof | 中国科学院化学研究所 | 2024-06-14 | — | — | CN | disclosed |
| EP-1150977-B1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | disclosed |
| US-6699879-B1 | OBESITY, DIABETES, SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-03-02 | — | — | US | disclosed |
| EP-1150977-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047577-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-17 | — | — | WO | disclosed |