Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | BRS3 | P32247 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579920 | 0.92 | EDNRA (0.46) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL8431636 | 0.92 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL8433247 | 0.91 | BRS3 (0.39) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL6580198 | 0.90 | EDNRA (0.44) | SMN1; SMN2ALDH1A1KDM4EHPGDEDNRA | |
| SCHEMBL8323946 | 0.88 | EDNRB (0.40) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL8329557 | 0.87 | MEN1 (0.39) | SMN1; SMN2ALDH1A1KDM4EHPGDEDNRA | |
| SCHEMBL8329904 | 0.87 | PPARG (0.38) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL6579951 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL8431530 | 0.84 | EDNRA (0.37) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD | |
| SCHEMBL8434942 | 0.84 | BRS3 (0.42) | SMN1; SMN2ALDH1A1BRS3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |