Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.36 |
| ▸ | CTSS | P25774 | 8/20 | 0.36 |
| ▸ | CTSB | P07858 | 6/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590230 | 0.92 | CTSK (0.35) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6588348 | 0.91 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6586665 | 0.89 | CTSL (0.40) | CTSKCTSLCTSS | |
| SCHEMBL6590972 | 0.89 | CTSK (0.37) | CTSKCTSLCTSSCTSBKLK5 | |
| SCHEMBL6593240 | 0.88 | CTSK (0.45) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6592491 | 0.87 | CTSK (0.38) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6588307 | 0.86 | CTSK (0.37) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6476585 | 0.86 | USP2 (0.43) | CTSKCTSLCTSS | |
| SCHEMBL6588604 | 0.86 | CTSK (0.38) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6589053 | 0.85 | CTSK (0.37) | CTSKCTSLCTSSCTSBKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |