Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588469 | 0.92 | CTSK (0.36) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6589005 | 0.92 | CTSK (0.44) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6586665 | 0.88 | CTSL (0.40) | CTSKCTSLCTSS | |
| SCHEMBL6590983 | 0.88 | CTSK (0.37) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6590972 | 0.87 | CTSK (0.37) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6593240 | 0.87 | CTSK (0.45) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6484505 | 0.86 | USP2 (0.46) | CTSKCTSLCTSS | |
| SCHEMBL6591090 | 0.85 | CTSK (0.36) | CTSKCTSLCTSSCTSBNAAA | |
| SCHEMBL6588604 | 0.84 | CTSK (0.38) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6588348 | 0.83 | CTSK (0.46) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |