SCHEMBL6589153

SCHEMBL6589153

CC1CC(c2cc(Cl)c(O)c(C(C)(C)C)c2)CC(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
HIF1A Q16665 1/20 0.33
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
CYP1A2 P05177 1/20 0.31
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6589150 1.00 CA2 (0.34) CA2CA1CYP2C9CYP2C19SMN1; SMN2
SCHEMBL6589658 0.90 CA2 (0.43) CA2CA1CYP2C9CYP2C19SMN1; SMN2
SCHEMBL6589660 0.90 CA2 (0.43) CA2CA1CYP2C9CYP2C19SMN1; SMN2
SCHEMBL6586417 0.87 ALDH1A1 (0.34) CYP2C9CYP2C19CYP1A2ALDH1A1
SCHEMBL6586422 0.87 ALDH1A1 (0.34) CYP2C9CYP2C19CYP1A2ALDH1A1
SCHEMBL6589256 0.84 IGF1R (0.35) CA2CA1CYP2C9CYP2C19SMN1; SMN2
SCHEMBL6589257 0.84 IGF1R (0.35) CA2CA1CYP2C9CYP2C19SMN1; SMN2
SCHEMBL6592372 0.82 ALDH1A1 (0.32) CYP2C9CYP2C19CYP1A2ALDH1A1
SCHEMBL6592376 0.82 ALDH1A1 (0.32) CYP2C9CYP2C19CYP1A2ALDH1A1
SCHEMBL7064838 0.82 CA1 (0.33) CA2CA1MGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-101472995-B Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-28 CN disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101472995-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101400763-A Halogen-free polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP (NL) 2009-04-01 CN disclosed
CN-101384684-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (US) 2009-03-11 CN disclosed
CN-101379114-A Thermally stable polycarbonates, thermoplastic compositions thereof, and articles made therefrom GEN ELECTRIC (US) 2009-03-04 CN disclosed
CN-101356235-A Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GEN ELECTRIC (US) 2009-01-28 CN disclosed
EP-1414888-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
EP-1414887-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
WO-2003010220-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed