SCHEMBL6589660

SCHEMBL6589660

CC1CC(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC(C)(C)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.43
CA1 P00915 2/20 0.43
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36
GALR3 O60755 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
HPN P05981 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
SIRT5 Q9NXA8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6589658 1.00 CA2 (0.43) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL6589150 0.90 CA2 (0.34) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL6589153 0.90 CA2 (0.34) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL6589256 0.90 IGF1R (0.35) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL6589257 0.90 IGF1R (0.35) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL7064838 0.88 CA1 (0.33) CA2CA1MGAMSIGAA
SCHEMBL6590729 0.84 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2POLBTYRHTT
SCHEMBL6590732 0.84 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2POLBTYRHTT
SCHEMBL6588666 0.80 ALDH1A1 (0.35) CA2CA1ALDH1A1HTTCYP1A2
SCHEMBL6588660 0.80 ALDH1A1 (0.35) CA2CA1ALDH1A1HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-111868612-A Polycarbonate having electro-optical effect, method for producing same, and light control element using same 帝人株式会社 2020-10-30 CN disclosed
CN-1914248-B Process for the production of copolycarbonates with reduced color GEN ELECTRIC 2011-04-06 CN disclosed
CN-100554309-C Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (NL) 2009-10-28 CN disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101384684-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (US) 2009-03-11 CN disclosed
CN-101379114-A Thermally stable polycarbonates, thermoplastic compositions thereof, and articles made therefrom GEN ELECTRIC (US) 2009-03-04 CN disclosed
CN-101356235-A Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GEN ELECTRIC (US) 2009-01-28 CN disclosed
CN-1914248-A Process for the production of copolycarbonates with reduced color GEN ELECTRIC (US) 2007-02-14 CN disclosed
CN-1694914-A Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (US) 2005-11-09 CN disclosed
EP-1414887-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed