Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | RBP4 | P02753 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747616 | 0.84 | GPR119 (0.54) | GPR119RBP4KDM4EPKMNAMPT | |
| SCHEMBL6321078 | 0.80 | RBP4 (0.66) | GPR119RBP4 | |
| SCHEMBL3436365 | 0.77 | GPR119 (0.58) | GPR119KDM4EPKMNAMPTMEN1 | |
| SCHEMBL2191425 | 0.77 | GPR119 (0.57) | GPR119KDM4EPKMNAMPTMEN1 | |
| SCHEMBL29805245 | 0.77 | GPR119 (0.57) | GPR119KDM4EPKMNAMPTMEN1 | |
| SCHEMBL21953943 | 0.76 | GPR119 (0.56) | GPR119KDM4EPKMNAMPTMEN1 | |
| SCHEMBL1613087 | 0.76 | GPR119 (0.56) | GPR119KDM4EPKMNAMPTTHRB | |
| SCHEMBL17871674 | 0.76 | ALDH1A1 (0.52) | RBP4KDM4E | |
| SCHEMBL6589130 | 0.76 | CHRM3 (0.58) | RBP4 | |
| SCHEMBL2102993 | 0.76 | GPR119 (0.53) | GPR119KDM4EPKMNAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |