Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.40 |
| ▸ | CTSL | P07711 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765719 | 0.87 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096443 | 0.81 | CTSK (0.41) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6592603 | 0.81 | CACNA1B (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6593138 | 0.73 | CTSL (0.31) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7246379 | 0.71 | — | — | |
| SCHEMBL6762057 | 0.71 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6762056 | 0.71 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6211744 | 0.70 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4765376 | 0.70 | CTSK (0.31) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7479129 | 0.70 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |