Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.41 |
| ▸ | QPCT | Q16769 | 6/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6591483 | 0.94 | GSK3B (0.37) | GSK3BQPCTADRB2PIM1CAMK2D | |
| SCHEMBL6588981 | 0.93 | CAMK2D (0.42) | GSK3BPIM1CAMK2DPLK1JAK2 | |
| Hydrochloric Acid SCHEMBL6588778 | 0.92 | CAMK2D (0.42) | GSK3BPIM1CAMK2DPLK1JAK2 | |
| SCHEMBL6586537 | 0.91 | PIM1 (0.40) | GSK3BPIM1CAMK2DPLK1 | |
| SCHEMBL6589065 | 0.90 | CAMK2D (0.40) | GSK3BQPCTPIM1CAMK2DPLK1 | |
| SCHEMBL6590083 | 0.90 | PIM1 (0.39) | GSK3BPIM1CAMK2DPLK1 | |
| Hydrochloric Acid SCHEMBL6589219 | 0.89 | CAMK2D (0.39) | GSK3BQPCTPIM1CAMK2DPLK1 | |
| Hydrochloric Acid SCHEMBL6598884 | 0.89 | CAMK2D (0.42) | GSK3BQPCTPIM1CAMK2DPLK1 | |
| Trifluoroacetic Acid SCHEMBL6588085 | 0.89 | GSK3B (0.36) | GSK3BQPCTPIM1CAMK2DPLK1 | |
| SCHEMBL6588432 | 0.88 | GSK3B (0.42) | GSK3BPIM1CAMK2DPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |