SCHEMBL6589418

SCHEMBL6589418

Nc1ccc(-c2ccccc2S(=O)(=O)O)cc1F

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.51
FEN1 P39748 19/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6171774 0.86 ALOX5AP (0.64) ALOX5APFEN1
SCHEMBL3828691 0.84 ALOX5AP (0.61) ALOX5APFEN1
Hydrochloric Acid SCHEMBL7230267 0.83 ALOX5AP (0.60) ALOX5APFEN1
SCHEMBL6236983 0.82 ALOX5AP (0.62) ALOX5APFEN1
SCHEMBL3546205 0.79 ALOX5AP (0.69) ALOX5APFEN1
SCHEMBL17557161 0.78 TTR (0.40) ALOX5APFEN1
SCHEMBL21000574 0.77 FEN1 (0.53) ALOX5APFEN1
SCHEMBL778751 0.76 PTGS2 (0.53) ALOX5APFEN1
SCHEMBL9818537 0.76 GNG2 (0.47) ALOX5APFEN1
SCHEMBL11037614 0.76 IKBKB (0.43) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465864-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE Warner-Lambert Company LLC (US) 2004-10-13 EP disclosed
WO-2003045912-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER-LAMBERT COMPANY LLC (US) 2003-06-05 WO disclosed