Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.39 |
| ▸ | FEN1 | P39748 | 13/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GNG2 | P59768 | 1/20 | 0.37 |
| ▸ | GNB1 | P62873 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037614 | 0.79 | IKBKB (0.43) | TTRALOX5APFEN1DDX3X | |
| SCHEMBL6589418 | 0.78 | ALOX5AP (0.51) | ALOX5APFEN1 | |
| SCHEMBL17557154 | 0.77 | PARP1 (0.42) | CYP1A2CYP2C9HSD17B10MEN1ALDH1A1 | |
| SCHEMBL9818537 | 0.76 | GNG2 (0.47) | TTRALOX5APFEN1CYP1A2CYP2C9 | |
| SCHEMBL31213502 | 0.76 | ALDH1A1 (0.50) | TTRALOX5APFEN1CYP1A2CYP2C9 | |
| SCHEMBL9169234 | 0.73 | APP (0.47) | ALOX5APFEN1HSD17B10MEN1APP | |
| SCHEMBL9507935 | 0.73 | GSTP1 (0.53) | CYP1A2CYP2C9PGAM1 | |
| SCHEMBL6174726 | 0.73 | ALOX5AP (0.50) | ALOX5APFEN1CYP2C9APPPTGES2 | |
| SCHEMBL8597480 | 0.72 | PTGS2 (0.47) | HSD17B10MEN1ALDH1A1MAPTTHRB | |
| SCHEMBL15849847 | 0.72 | PTGS2 (0.47) | HSD17B10MEN1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884866-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-02-06 | — | — | US | disclosed |
| US-20160068533-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068533-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | CD40, CD47, FCGRT | TTR 1474/4885ALOX5AP 1811/4885FEN1 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.