Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 8/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASK | O14936 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6586548 | 0.97 | CAMK2D (0.50) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6587901 | 0.94 | CAMK2D (0.46) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6591485 | 0.94 | CAMK2D (0.44) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6586721 | 0.93 | CAMK2D (0.43) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6585782 | 0.93 | CAMK2D (0.45) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6588330 | 0.93 | CAMK2D (0.43) | CAMK2DPIM1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6588255 | 0.91 | CAMK2D (0.43) | CAMK2DPIM1PRKCAGSK3B | |
| Trifluoroacetic Acid SCHEMBL6586373 | 0.87 | IDO1 (0.36) | CAMK2DPIM1PRKCAGSK3B | |
| Trifluoroacetic Acid SCHEMBL6588835 | 0.87 | CHEK1 (0.39) | CAMK2DPIM1CDK2PRKCAGSK3B | |
| SCHEMBL6588231 | 0.85 | CAMK2D (0.51) | CAMK2DPIM1RPS6KB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1183252-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071537-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-30 | — | — | WO | disclosed |