Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6588330 | 0.97 | CAMK2D (0.43) | CAMK2DPIM1PTGDR2CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6586721 | 0.94 | CAMK2D (0.43) | CAMK2DPIM1CA12CA1CA2 | |
| SCHEMBL6588231 | 0.94 | CAMK2D (0.51) | CAMK2DPIM1PDK1 | |
| Trifluoroacetic Acid SCHEMBL6587901 | 0.93 | CAMK2D (0.46) | CAMK2DPIM1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6591980 | 0.93 | ICMT (0.37) | CAMK2DPIM1PTGDR2HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6589561 | 0.93 | CAMK2D (0.50) | CAMK2DPIM1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6586877 | 0.92 | ICMT (0.38) | CAMK2DPIM1PTGDR2HSP90AA1CCNT1 | |
| Trifluoroacetic Acid SCHEMBL6584844 | 0.92 | CAMK2D (0.37) | CAMK2DPIM1PTGDR2HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6590532 | 0.91 | CDK2 (0.38) | CAMK2DPIM1PTGDR2HSP90AA1CDK2 | |
| Trifluoroacetic Acid SCHEMBL6590147 | 0.91 | HSP90AA1 (0.38) | CAMK2DPIM1PTGDR2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |