⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6589094 | 0.94 | HTR1A (0.60) | — | |
| SCHEMBL1037297 | 0.85 | — | — | |
| SCHEMBL1038535 | 0.85 | — | — | |
| SCHEMBL6591599 | 0.84 | HTR1A (0.60) | — | |
| SCHEMBL6588430 | 0.83 | — | — | |
| SCHEMBL6591927 | 0.82 | — | — | |
| SCHEMBL9175923 | 0.81 | — | — | |
| Oxalic Acid SCHEMBL6776732 | 0.80 | HTR1A (0.55) | — | |
| SCHEMBL9178367 | 0.79 | ALDH1A1 (0.64) | — | |
| SCHEMBL9176472 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007523-B9 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2004-09-08 | — | — | EP | claimed |
| EP-1007523-B1 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2003-10-22 | — | — | EP | claimed |
| US-6476035-B1 | Indole and 2,3-dihydroindole derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2002-11-05 | — | — | US | claimed |
| CN-1265107-A | indole and 2, 3-indoline derivatives, their preparation and use | LUNDBECK & CO AS H (DK) | 2000-08-30 | — | — | CN | claimed |
| EP-1007523-B9 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2004-09-08 | — | — | EP | disclosed |
| CN-1515569-A | Indole and 2,3-indoline derivative, their preparation and application | H.隆德贝克有限公司 | 2004-07-28 | — | — | CN | disclosed |
| CN-1515568-A | Indole and 2,3-indoline derivative, their preparation and application | H.隆德贝克有限公司 | 2004-07-28 | — | — | CN | disclosed |
| US-6727263-B2 | SEROTONINE REUPTAKE INHIBITOR; ANTIDEPRESSANTS; SIDE EFFECT REDUCTION | H. LUNDBECK A/S (DK) | 2004-04-27 | — | — | US | disclosed |
| CN-1127501-C | indole and 2, 3-indoline derivatives, their preparation and use | LUNDBECK & CO AS H (DK) | 2003-11-12 | — | — | CN | disclosed |
| EP-1007523-B1 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2003-10-22 | — | — | EP | disclosed |
| US-20030018050-A1 | Indole and 2,3-dihydroindole derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2003-01-23 | — | — | US | disclosed |
| US-6476035-B1 | Indole and 2,3-dihydroindole derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2002-11-05 | — | — | US | disclosed |
| CN-1265107-A | indole and 2, 3-indoline derivatives, their preparation and use | LUNDBECK & CO AS H (DK) | 2000-08-30 | — | — | CN | disclosed |