Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31074036 | 0.80 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5737282 | 0.80 | KDM4E (0.56) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5145111 | 0.79 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2222010 | 0.78 | ALDH1A1 (0.62) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5166572 | 0.76 | GSK3A (0.69) | MAPTKMT2AMEN1LMNARECQL | |
| SCHEMBL5166576 | 0.76 | GSK3A (0.69) | MAPTKMT2AMEN1LMNARECQL | |
| SCHEMBL7833840 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4704691 | 0.76 | LDHA (0.64) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2559176 | 0.76 | MAPT (0.67) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2559177 | 0.76 | MAPT (0.67) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |