Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.72 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314420 | 0.88 | SIGMAR1 (0.76) | SIGMAR1HTR1AS1PR1S1PR3KCNA3 | |
| SCHEMBL9531074 | 0.86 | SIGMAR1 (0.74) | SIGMAR1HTR1A | |
| SCHEMBL10974420 | 0.83 | PPARG (0.55) | SIGMAR1KCNA3MEN1KMT2AKDM4E | |
| SCHEMBL10231292 | 0.82 | SIGMAR1 (0.68) | SIGMAR1HTR1AS1PR1S1PR3MEN1 | |
| Hydrochloric Acid SCHEMBL10734491 | 0.82 | PPARG (0.54) | SIGMAR1KCNA3MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8970558 | 0.81 | SIGMAR1 (0.87) | SIGMAR1 | |
| SCHEMBL29363627 | 0.80 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL29710461 | 0.79 | SIGMAR1 (0.85) | SIGMAR1HTR1A | |
| SCHEMBL4485693 | 0.79 | DRD2 (0.54) | SIGMAR1HTR1AKCNA3KDM4EMAPT | |
| SCHEMBL27801629 | 0.78 | KDM4E (0.56) | SIGMAR1HTR1AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458688-A1 | QUINAZOLINONE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055865-A1 | QUINAZOLINONE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-10 | — | — | WO | disclosed |