Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.39 |
| ▸ | CTSS | P25774 | 15/20 | 0.39 |
| ▸ | CTSL | P07711 | 12/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587905 | 0.91 | CTSK (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6591065 | 0.90 | CTSK (0.38) | CTSKCTSSCTSLCTSBUTS2R | |
| SCHEMBL6594368 | 0.89 | CTSS (0.45) | CTSKCTSSCTSL | |
| SCHEMBL6476369 | 0.88 | CTSS (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6590578 | 0.88 | CTSS (0.37) | CTSKCTSSCTSLCTSBUTS2R | |
| SCHEMBL6590048 | 0.87 | CTSS (0.39) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6591783 | 0.87 | CTSL (0.40) | CTSKCTSSCTSL | |
| SCHEMBL6587320 | 0.87 | CTSL (0.38) | CTSKCTSSCTSL | |
| SCHEMBL6592500 | 0.86 | CTSK (0.37) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6476624 | 0.83 | CTSK (0.51) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |