Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.66 |
| ▸ | MMP3 | P08254 | 10/20 | 0.66 |
| ▸ | MMP1 | P03956 | 2/20 | 0.66 |
| ▸ | MMP9 | P14780 | 2/20 | 0.66 |
| ▸ | MMP14 | P50281 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588282 | 0.96 | MMP2 (0.67) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586529 | 0.94 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6965292 | 0.87 | MMP2 (0.67) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586414 | 0.87 | MMP2 (0.54) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6972711 | 0.82 | MMP2 (0.60) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587292 | 0.82 | MMP2 (0.58) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6972911 | 0.81 | MMP2 (0.42) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6585851 | 0.80 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586686 | 0.78 | MMP2 (0.60) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586333 | 0.77 | MMP2 (0.85) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | claimed |