Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.46 |
| ▸ | CTSS | P25774 | 17/20 | 0.46 |
| ▸ | CTSL | P07711 | 14/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590184 | 0.92 | CTSS (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6593578 | 0.91 | CTSK (0.40) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6591065 | 0.91 | CTSK (0.38) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6587905 | 0.89 | CTSK (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6594456 | 0.88 | CTSL (0.47) | CTSKCTSSCTSL | |
| SCHEMBL6482898 | 0.88 | CTSS (0.49) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6593924 | 0.86 | CTSS (0.55) | CTSKCTSSCTSL | |
| SCHEMBL6591830 | 0.84 | CTSL (0.47) | CTSKCTSSCTSL | |
| SCHEMBL6590578 | 0.83 | CTSS (0.37) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6590456 | 0.83 | CTSS (0.40) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |