Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590360 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3554224 | 0.83 | HTT (0.40) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3554226 | 0.83 | HTT (0.40) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6593013 | 0.78 | MAPT (0.36) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6593008 | 0.78 | MAPT (0.36) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3551267 | 0.78 | MAPT (0.36) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6593940 | 0.78 | MAPT (0.37) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6593945 | 0.78 | MAPT (0.37) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3551270 | 0.78 | MAPT (0.36) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6598299 | 0.77 | CYP1A2 (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351958-B1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-06-16 | — | — | EP | disclosed |