Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.49 |
| ▸ | CTSL | P07711 | 10/20 | 0.49 |
| ▸ | CTSS | P25774 | 9/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594376 | 0.92 | CTSS (0.58) | CTSKCTSLCTSSCTSBNFKB1 | |
| SCHEMBL6591732 | 0.90 | CTSL (0.62) | CTSKCTSLCTSS | |
| SCHEMBL6588896 | 0.90 | CTSK (0.51) | CTSKCTSLCTSS | |
| SCHEMBL6590280 | 0.87 | CTSK (0.47) | CTSKCTSLCTSSCTSBNFKB1 | |
| SCHEMBL6590299 | 0.86 | CTSL (0.51) | CTSKCTSLCTSS | |
| SCHEMBL6594147 | 0.86 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6592330 | 0.86 | CTSK (0.43) | CTSKCTSLCTSS | |
| SCHEMBL6590768 | 0.85 | CTSL (0.50) | CTSKCTSLCTSS | |
| SCHEMBL6590249 | 0.85 | CTSL (0.42) | CTSKCTSLCTSS | |
| SCHEMBL6591197 | 0.85 | CTSL (0.39) | CTSKCTSLCTSSCTSBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |