Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.66 |
| ▸ | PPARA | Q07869 | 13/20 | 0.66 |
| ▸ | PPARD | Q03181 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990917 | 0.89 | PPARA (0.55) | PPARGPPARAPPARDKDM4EKMT2A | |
| SCHEMBL13793229 | 0.89 | PPARA (0.55) | PPARGPPARAPPARDKDM4EKMT2A | |
| SCHEMBL7299495 | 0.88 | SRR (0.57) | PPARGPPARA | |
| SCHEMBL7299501 | 0.88 | SRR (0.57) | PPARGPPARA | |
| SCHEMBL27653539 | 0.85 | PPARG (0.67) | PPARGPPARAPPARDKDM4EKMT2A | |
| SCHEMBL24328378 | 0.82 | SRR (0.61) | PPARGPPARA | |
| Cyclohexylamine SCHEMBL5607970 | 0.81 | PPARA (0.58) | PPARGPPARAPPARDKDM4EFFAR1 | |
| SCHEMBL288435 | 0.80 | PPARA (0.74) | PPARGPPARAPPARDFFAR1FFAR4 | |
| SCHEMBL6713386 | 0.80 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL5606931 | 0.80 | PPARA (0.74) | PPARGPPARAPPARDFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453811-A2 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048130-A2 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |