SCHEMBL24328378

SCHEMBL24328378

O=C(O)[C@H](Cc1ccccc1)OC1CC1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 2/20 0.61
PPARG P37231 17/20 0.53
PPARA Q07869 15/20 0.53
ACE P12821 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7299501 0.93 SRR (0.57) SRRPPARGPPARAACE
SCHEMBL7299495 0.93 SRR (0.57) SRRPPARGPPARAACE
SCHEMBL24328381 0.88 SLC7A5 (0.49) SRRPPARGPPARA
Hydrochloric Acid SCHEMBL7302958 0.88 SRR (0.54) SRRPPARGPPARAACE
SCHEMBL24328380 0.87 PPARG (0.57) SRRPPARGPPARA
SCHEMBL6590735 0.82 PPARG (0.66) PPARGPPARA
SCHEMBL3430510 0.80 SRR (0.50) SRRPPARGPPARA
SCHEMBL24301971 0.78 SMN1; SMN2 (0.66) ACE
SCHEMBL13311342 0.78 SRR (0.48) SRRPPARGPPARA
SCHEMBL6487486 0.78 SRR (0.48) SRRPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS SRR 3147/4885PPARG 1211/4885PPARA 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.