Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529053 | 0.88 | MEN1 (0.51) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL7106623 | 0.77 | TUBB4A (0.43) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6343105 | 0.76 | CYP19A1 (0.44) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL6351443 | 0.74 | TUBB4A (0.47) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL6346701 | 0.72 | PTGS2 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL731067 | 0.70 | PRKCQ (0.52) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL10282804 | 0.69 | TUBB4A (0.77) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4339872 | 0.69 | MAP3K11 (0.63) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL15758953 | 0.68 | MEN1 (0.55) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL29260924 | 0.68 | TUBB1 (0.67) | MEN1KMT2ATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181269-B1 | CELL PROLIFERATION INHIBITORS | ABBOTT LAB (US) | 2004-02-25 | — | — | EP | claimed |