Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590873 | 0.88 | MEN1 (0.51) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL7465572 | 0.74 | CA2 (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL731067 | 0.70 | PRKCQ (0.52) | MEN1KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL31234464 | 0.69 | CA12 (0.60) | CA12CA1CA2CA9MAP3K11 | |
| SCHEMBL4339872 | 0.69 | MAP3K11 (0.63) | MEN1KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL15758953 | 0.68 | MEN1 (0.55) | MEN1KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL30667621 | 0.68 | CA12 (0.55) | CA12CA1CA2CA9LRRK2 | |
| SCHEMBL6341334 | 0.67 | TUBB4A (0.53) | MEN1KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL10282804 | 0.67 | TUBB4A (0.77) | MEN1KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL7084967 | 0.67 | NPC1 (0.53) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | disclosed |