Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.69 |
| ▸ | MMP2 | P08253 | 13/20 | 0.69 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP14 | P50281 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588468 | 0.92 | MMP3 (0.58) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6587821 | 0.90 | MMP3 (0.73) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6435682 | 0.89 | MMP3 (0.59) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6587846 | 0.84 | MMP2 (0.83) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL7408826 | 0.82 | MMP2 (0.82) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6585076 | 0.82 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP14 | |
| Dimethylamine SCHEMBL6437006 | 0.81 | MMP2 (0.80) | MMP3MMP2MMP1MMP9MMP14 | |
| Dimethylamine SCHEMBL6974207 | 0.80 | MMP3 (0.97) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6588532 | 0.80 | MMP2 (0.84) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6587889 | 0.78 | MMP2 (0.65) | MMP3MMP2MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |