Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590986 | 1.00 | MMP2 (0.42) | MMP2APPALDH1A1PDE4APDE4C | |
| SCHEMBL6080201 | 0.89 | APP (0.50) | MMP2APPALDH1A1PDE4APDE4C | |
| SCHEMBL6537497 | 0.78 | ALDH1A1 (0.52) | ALDH1A1PDE4APDE4CPDE4DALOX15 | |
| SCHEMBL6592928 | 0.76 | CTSV (0.47) | APPL3MBTL1 | |
| SCHEMBL6592924 | 0.76 | CTSV (0.47) | APPL3MBTL1 | |
| SCHEMBL6080203 | 0.76 | TSHR (0.40) | MMP2ALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL6596638 | 0.76 | MRGPRX4 (0.44) | MAPTL3MBTL1DHODH | |
| SCHEMBL6590529 | 0.76 | KMT2A (0.48) | ALDH1A1PDE4DGPR35ALOX15MEN1 | |
| SCHEMBL6080952 | 0.76 | KMT2A (0.48) | ALDH1A1PDE4DGPR35ALOX15MEN1 | |
| SCHEMBL6591021 | 0.74 | MEN1 (0.54) | ALDH1A1GPR35ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |