Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 7/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 7/20 | 0.33 |
| ▸ | RPS17 | P08708 | 7/20 | 0.33 |
| ▸ | RPSA | P08865 | 7/20 | 0.33 |
| ▸ | RPS2 | P15880 | 7/20 | 0.33 |
| ▸ | RPL35A | P18077 | 7/20 | 0.33 |
| ▸ | RPL7 | P18124 | 7/20 | 0.33 |
| ▸ | RPL17 | P18621 | 7/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 7/20 | 0.33 |
| ▸ | RPS3 | P23396 | 7/20 | 0.33 |
| ▸ | RPS12 | P25398 | 7/20 | 0.33 |
| ▸ | RPL13 | P26373 | 7/20 | 0.33 |
| ▸ | RPL10 | P27635 | 7/20 | 0.33 |
| ▸ | RPL12 | P30050 | 7/20 | 0.33 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 7/20 | 0.33 |
| ▸ | RPL22 | P35268 | 7/20 | 0.33 |
| ▸ | RPL4 | P36578 | 7/20 | 0.33 |
| ▸ | RPS19 | P39019 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971336 | 0.91 | IRAK4 (0.33) | PTGDR2KCNH2RPLP1RPLP0RPS17 | |
| SCHEMBL6590523 | 0.86 | SLC6A2 (0.30) | KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6594372 | 0.85 | RPLP1 (0.38) | KCNH2RPLP1RPLP0RPS17RPSA | |
| SCHEMBL4761997 | 0.84 | IRAK4 (0.33) | PTGDR2KCNH2RPLP1RPLP0RPS17 | |
| SCHEMBL4761916 | 0.83 | PSEN1 (0.33) | PTGDR2RPLP1RPLP0RPS17RPSA | |
| SCHEMBL6764532 | 0.83 | CTSK (0.33) | PTGDR2KCNH2RPLP1RPLP0RPS17 | |
| SCHEMBL6205886 | 0.81 | — | — | |
| SCHEMBL5970851 | 0.81 | RPS6KB1 (0.33) | KCNH2 | |
| SCHEMBL7425666 | 0.81 | CYP3A4 (0.32) | EP300 | |
| SCHEMBL7009758 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |