Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588480 | 0.91 | IRAK4 (0.31) | — | |
| SCHEMBL4768508 | 0.83 | EP300 (0.30) | EP300 | |
| SCHEMBL6591072 | 0.81 | PTGDR2 (0.33) | EP300 | |
| SCHEMBL6594372 | 0.80 | RPLP1 (0.38) | — | |
| SCHEMBL6589335 | 0.79 | — | — | |
| SCHEMBL6590523 | 0.77 | SLC6A2 (0.30) | — | |
| SCHEMBL6590675 | 0.75 | TNKS (0.31) | — | |
| SCHEMBL4765922 | 0.74 | — | — | |
| SCHEMBL5971336 | 0.73 | IRAK4 (0.33) | — | |
| SCHEMBL6589694 | 0.71 | SIGMAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |