Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.32 |
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | RPLP1 | P05386 | 3/20 | 0.32 |
| ▸ | RPLP0 | P05388 | 3/20 | 0.32 |
| ▸ | RPS17 | P08708 | 3/20 | 0.32 |
| ▸ | RPSA | P08865 | 3/20 | 0.32 |
| ▸ | RPS2 | P15880 | 3/20 | 0.32 |
| ▸ | RPL35A | P18077 | 3/20 | 0.32 |
| ▸ | RPL7 | P18124 | 3/20 | 0.32 |
| ▸ | RPL17 | P18621 | 3/20 | 0.32 |
| ▸ | RPS4Y1 | P22090 | 3/20 | 0.32 |
| ▸ | RPS3 | P23396 | 3/20 | 0.32 |
| ▸ | RPS12 | P25398 | 3/20 | 0.32 |
| ▸ | RPL13 | P26373 | 3/20 | 0.32 |
| ▸ | RPL10 | P27635 | 3/20 | 0.32 |
| ▸ | RPL12 | P30050 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426317 | 0.86 | CTSK (0.37) | CTSKPTGDR2CTSLCTSSRPLP1 | |
| SCHEMBL5096405 | 0.83 | CTSK (0.35) | CTSKPTGDR2CTSLCTSSCIT | |
| SCHEMBL6591072 | 0.83 | PTGDR2 (0.33) | PTGDR2RPLP1RPLP0RPS17RPSA | |
| SCHEMBL6590370 | 0.82 | AAK1 (0.36) | PTGDR2ALOX5APFEN1 | |
| SCHEMBL5971691 | 0.82 | MAPK1 (0.36) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7428571 | 0.81 | RPLP1 (0.33) | PTGDR2ALOX5APFEN1RPLP1RPLP0 | |
| SCHEMBL7534924 | 0.81 | CTSK (0.42) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4761997 | 0.80 | IRAK4 (0.33) | PTGDR2RPLP1RPLP0RPS17RPSA | |
| SCHEMBL5971336 | 0.80 | IRAK4 (0.33) | PTGDR2RPLP1RPLP0RPS17RPSA | |
| SCHEMBL7428041 | 0.80 | CTSK (0.41) | CTSKCTSLCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002487-A1 | Protease inhibitors | MARQUIS ROBERT WELLS (US) | 2004-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002487-A1 | Protease inhibitors | CTSK, MMP13, CTSZ | CTSK 1/4885PTGDR2 2737/4885CTSL 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.