SCHEMBL659207

SCHEMBL659207

C=Cc1ccc(C=CC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
CYP3A4 P08684 4/20 0.52
TSHR P16473 2/20 0.52
TP53 P04637 2/20 0.52
LMNA P02545 1/20 0.52
KDM4E B2RXH2 1/20 0.52
HDAC8 Q9BY41 2/20 0.44
CNR2 P34972 1/20 0.43
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
TYR P14679 1/20 0.38
TRPA1 O75762 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372946 1.00 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRTP53LMNA
SCHEMBL659206 1.00 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRTP53LMNA
4-Vinylphenol SCHEMBL17478290 0.89 APP (0.48) ALDH1A1CYP3A4TSHRTP53LMNA
Styrene SCHEMBL28409227 0.87 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRTP53LMNA
Styrene SCHEMBL499427 0.87 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRTP53LMNA
Styrene SCHEMBL11264136 0.85 ALDH1A1 (0.64) ALDH1A1CYP3A4TSHRTP53LMNA
SCHEMBL7527708 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4TSHRTP53LMNA
SCHEMBL9461723 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4TSHRTP53LMNA
SCHEMBL333123 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4TSHRTP53LMNA
Styrene SCHEMBL8161392 0.84 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRTP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150322186-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY PENN STATE RES FOUND (US) 2015-11-12 US claimed
US-9109057-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2015-08-18 US claimed
CN-104419104-A Eraser-like cleaner SEED CO LTD 2015-03-18 CN claimed
CN-104419103-A Eraser-type cleaner SEED CO LTD 2015-03-18 CN claimed
CN-103562305-A Thermoplastic elastomers moldable under low shear conditions POLYONE CORP 2014-02-05 CN claimed
CN-101796127-B Flame retardant thermoplastic elastomers POLYONE CORP 2013-10-30 CN claimed
CN-102869722-A Super-soft thermoplastic elastomers POLYONE CORP 2013-01-09 CN claimed
WO-2012024614-A2 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2012-02-23 US claimed
CN-101796127-A Flame retardant thermoplastic elastomers POLYONE CORP 2010-08-04 CN claimed
CN-101098921-A Use of carbon nanotubes for preparing electrically conductive organic compositions and use of such compositions ARKEMA FRANCE (FR) 2008-01-02 CN claimed
WO-2001042259-A1 1,6,6-TRIAZACYCLOHEXANE COORDINATION COMPOUNDS FOR THE PREPARATION OF METAL CONTAINING POLYMERS BRITISH NUCLEAR FUELS PLC (GB) 2001-06-14 WO claimed
CN-119735748-A Preparation method of polymer with ring-chain hybridization structure and polymer with ring-chain hybridization structure 清华大学 2025-04-01 CN disclosed
CN-108271378-B Polyolefin interpenetrating network material for hydrocarbon recovery 宾夕法尼亚州立大学研究基金会 2020-07-31 CN disclosed
EP-3350238-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY The Penn State Research Foundation (US) 2018-07-25 EP disclosed
US-9861954-B2 Polyolefin interpenetrated network material for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2018-01-09 US disclosed
WO-2001042259-A1 1,6,6-TRIAZACYCLOHEXANE COORDINATION COMPOUNDS FOR THE PREPARATION OF METAL CONTAINING POLYMERS BRITISH NUCLEAR FUELS PLC (GB) 2001-06-14 WO disclosed
CN-1124247-A Preparation of polyalkyl-1-*-bi-nitrogen-hetero-helidecane compound HOECHST AG (DE) 1996-06-12 CN disclosed
US-4882219-A Crack resistant coating for masonry structures THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-11-21 US disclosed
US-4804693-A Crack resistant coating for masonry structures THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY LIPA, HSPH1, HPGDS ALDH1A1 3406/4885CYP3A4 1408/4885TSHR 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.