Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.46 |
| ▸ | RARA | P10276 | 12/20 | 0.46 |
| ▸ | RARG | P13631 | 11/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590206 | 0.92 | RARA (0.40) | RARBRARARARGPPARAPPARG | |
| SCHEMBL6592120 | 0.90 | RARA (0.52) | RARBRARARARGPPARG | |
| SCHEMBL6596504 | 0.87 | RARA (0.60) | RARBRARARARGRXRA | |
| SCHEMBL6587693 | 0.85 | RARA (0.45) | RARBRARARARGPPARACYP2D6 | |
| SCHEMBL6590527 | 0.80 | RARA (0.48) | RARBRARARARGPPARAPPARG | |
| SCHEMBL8331104 | 0.76 | RARA (0.41) | RARBRARARARGPPARAPPARG | |
| SCHEMBL6593231 | 0.75 | RARA (0.67) | RARBRARARARG | |
| SCHEMBL6592317 | 0.75 | RARA (0.56) | RARBRARARARGOPRD1 | |
| SCHEMBL8125785 | 0.74 | RARA (0.42) | RARBRARARARGPPARAKCNH2 | |
| SCHEMBL24727649 | 0.73 | RARB (0.52) | RARBRARARARGCYP2D6OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042313-B1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY | ALLERGAN INC (US) | 2004-04-28 | — | — | EP | disclosed |