Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 4/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332455 | 0.92 | RARA (0.44) | RARARARBRARGLTB4R2PPARA | |
| SCHEMBL8331802 | 0.90 | RARA (0.52) | RARARARBRARGLTB4R2PPARG | |
| SCHEMBL8335176 | 0.88 | RARB (0.41) | RARARARBRARGPPARAPPARG | |
| SCHEMBL8329425 | 0.88 | RARA (0.41) | RARARARBRARGLTB4R2OPRD1 | |
| SCHEMBL6592227 | 0.76 | RARB (0.46) | RARARARBRARGPPARAPPARG | |
| SCHEMBL6596504 | 0.74 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL24727655 | 0.73 | RARB (0.52) | RARARARBRARGOPRD1KCNH2 | |
| SCHEMBL8333207 | 0.70 | RARB (0.38) | RARARARBRARGRAB9ASMN1; SMN2 | |
| SCHEMBL8331248 | 0.69 | RARB (0.38) | RARARARBRARG | |
| SCHEMBL6590527 | 0.68 | RARA (0.48) | RARARARBRARGPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |