Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385707 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL13385526 | 0.78 | L3MBTL1 (0.53) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL657980 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL10287703 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL657537 | 0.76 | PDPK1 (0.56) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL2176604 | 0.75 | L3MBTL1 (0.44) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL656363 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL657072 | 0.72 | ALDH1A1 (0.51) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL10309640 | 0.70 | KMT2A (0.55) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL16488408 | 0.70 | KMT2A (0.55) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | ALDH1A1 4784/4885CYP1A2 4611/4885HPGD 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.