Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080624 | 0.90 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1MAPTPTPN1 | |
| SCHEMBL6080604 | 0.86 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1MAPTIKBKB | |
| SCHEMBL6595828 | 0.84 | MRGPRX4 (0.44) | PTPN1MCL1MAP4K4KMO | |
| SCHEMBL6594732 | 0.83 | MCL1 (0.49) | PTPN1MCL1MAP4K4 | |
| SCHEMBL6588409 | 0.82 | MCL1 (0.46) | PTPN1MCL1MAP4K4KMO | |
| SCHEMBL6592298 | 0.82 | MCL1 (0.53) | MAPTPTPN1MCL1MAP4K4 | |
| SCHEMBL6080629 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1MAPTMCL1 | |
| SCHEMBL6080980 | 0.81 | L3MBTL1 (0.53) | CYP11B1CYP11B2CYP19A1L3MBTL1KMO | |
| SCHEMBL6590308 | 0.80 | MAPT (0.42) | MAPTPTPN1MCL1MAP4K4 | |
| SCHEMBL6594866 | 0.79 | PTGER1 (0.44) | MAPTMCL1MAP4K4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |