Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080550 | 0.92 | MAPT (0.45) | MCL1MAPTNPSR1CTSLCTSB | |
| SCHEMBL6594732 | 0.88 | MCL1 (0.49) | MCL1PTPN1MAP4K4 | |
| SCHEMBL6591608 | 0.86 | MCL1 (0.51) | MCL1MAPTMAPK1 | |
| SCHEMBL6588409 | 0.84 | MCL1 (0.46) | MCL1PTPN1MAP4K4DHODH | |
| SCHEMBL6595828 | 0.84 | MRGPRX4 (0.44) | MCL1PTPN1MAP4K4DHODH | |
| SCHEMBL6080319 | 0.82 | CNR1 (0.46) | MCL1MAPTPTPN1PPARDMAP4K4 | |
| SCHEMBL6593585 | 0.82 | CYP11B1 (0.47) | MCL1MAPTPTPN1MAP4K4 | |
| SCHEMBL6595262 | 0.81 | ALOX15 (0.51) | MCL1DHODH | |
| SCHEMBL6079891 | 0.81 | MCL1 (0.53) | MCL1MAPTNPSR1MAPK1 | |
| SCHEMBL6590308 | 0.80 | MAPT (0.42) | MCL1MAPTPTPN1PPARDMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |