Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TYMS | P04818 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593981 | 1.00 | TNF (0.35) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL6597409 | 0.77 | PDE3B (0.44) | MEN1KMT2AFABP4HPGDALDH1A1 | |
| SCHEMBL6597415 | 0.77 | PDE3B (0.44) | MEN1KMT2AFABP4HPGDALDH1A1 | |
| SCHEMBL6594327 | 0.77 | TNF (0.61) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL6661728 | 0.71 | TNF (0.39) | TNFNOD1MEN1KMT2AHPGD | |
| SCHEMBL6664825 | 0.71 | TNF (0.39) | TNFNOD1MEN1KMT2AHPGD | |
| SCHEMBL6589681 | 0.71 | KDM4E (0.63) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL6589679 | 0.71 | KDM4E (0.63) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL15347362 | 0.70 | ALDH1A1 (0.47) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL15347361 | 0.70 | ALDH1A1 (0.47) | TNFNOD1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |