Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080943 | 0.90 | FFAR1 (0.40) | FFAR1MAP4K4 | |
| SCHEMBL6593903 | 0.85 | P2RY14 (0.46) | MCL1MAP4K4PTGER1XDH | |
| SCHEMBL6613626 | 0.82 | PTGER1 (0.41) | MCL1FFAR1PTGER1P4HTM | |
| SCHEMBL6596767 | 0.82 | MRGPRX4 (0.47) | MCL1MAP4K4PTGER1P4HTMMRGPRX4 | |
| SCHEMBL6596585 | 0.79 | THRA (0.45) | MCL1PTGER1P4HTM | |
| SCHEMBL6592323 | 0.78 | MCL1 (0.48) | MCL1PTGER1XDH | |
| SCHEMBL6590520 | 0.77 | MRGPRX4 (0.47) | MCL1PTGER1P4HTMMRGPRX4 | |
| SCHEMBL6080945 | 0.76 | KDM4E (0.36) | MCL1FFAR1MAP4K4P4HTM | |
| SCHEMBL6598155 | 0.76 | PTGER1 (0.50) | MCL1PTGER1MRGPRX4 | |
| SCHEMBL2908552 | 0.76 | ALOX15 (0.64) | MCL1PTGER1P4HTMMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |