Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960185 | 0.76 | ALDH1A1 (0.51) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10470286 | 0.74 | PTPN1 (0.56) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3954390 | 0.73 | KMT2A (0.48) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL4608245 | 0.72 | CYP1A2 (0.48) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9052092 | 0.72 | KMT2A (0.51) | KMT2ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL8083816 | 0.71 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL11472411 | 0.70 | ALDH1A1 (0.53) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6594701 | 0.70 | KDM4E (0.49) | KMT2ACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL4634518 | 0.69 | KMT2A (0.52) | KMT2ASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL6586460 | 0.67 | ALDH1A1 (0.40) | KMT2ACYP1A2SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0927192-B1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-12 | — | — | EP | disclosed |