Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594911 | 1.00 | MAPT (0.58) | MAPTSMN1; SMN2MITFHTTALDH1A1 | |
| SCHEMBL6080758 | 0.87 | MAPT (0.54) | MAPTSMN1; SMN2MITFHTTALDH1A1 | |
| SCHEMBL6604563 | 0.82 | KDM4E (0.46) | MAPTHTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6600666 | 0.81 | NCF1 (0.49) | MAPTALDH1A1L3MBTL1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL6079350 | 0.81 | KDM4E (0.44) | MAPTHTTALDH1A1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL6080392 | 0.80 | NCF1 (0.48) | MAPTHTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6590529 | 0.77 | KMT2A (0.48) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL6080952 | 0.77 | KMT2A (0.48) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL6591021 | 0.76 | MEN1 (0.54) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL6591013 | 0.76 | MEN1 (0.54) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |